Hydride Reduction by a Sodium Hydride-Iodide Composite
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چکیده
منابع مشابه
Hydride Reduction by a Sodium Hydride–Iodide Composite
Sodium hydride (NaH) is widely used as a Brønsted base in chemical synthesis and reacts with various Brønsted acids, whereas it rarely behaves as a reducing reagent through delivery of the hydride to polar π electrophiles. This study presents a series of reduction reactions of nitriles, amides, and imines as enabled by NaH in the presence of LiI or NaI. This remarkably simple protocol endows Na...
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ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2016
ISSN: 0044-8249
DOI: 10.1002/ange.201600305